New Study – NSAIDS increase heart disease

Ben Dearman – KDR Fitness

Achy joints?


Think twice about popping an anti-inflammatory!

Researchers have known for more than a decade that the risk of heart disease and stroke increases when people take pain relievers like ibuprofen and other non-steroidal anti-inflammatory drugs, or NSAIDs. Now, scientists from the University of California, Davis, have uncovered some of the reasons why these drugs can harm heart tissue.

In a recent study published in the “Journal of Molecular and Cellular Cardiology” it was shown that non steroidal anti-inflammatories (NSAIDS) INCREASED the risk of heart disease.

WHA?!  How can that be?!

Well it was found, specifically in naproxen sodium (over the counter) and meclofenamate sodium (prescription) containing NSAIDS, that these specific molecules caused a few things to happen to the cells in heart tissue.

  1.  They increased ROS (reactive oxygen species) in cardiac tissue.  Think of ROS as rust in your body.  Just like rust can eat away at metal over time, ROS can reap havoc on your cells and cause pre-mature aging to happen.  Your heart is absolutely where you DO NOT want pre-mature aging to happen.
  2. NSAIDS specifically attacked the mitochondria in heart cells.  Mitochondria are the energy generators of the cell.  Every time a cardiac cell has to do something it relies on it’s mitochondria to produce the energy necessary to do the “thing”.  If a cells mitochondria become compromised that cell is close to dying.
  3. Impair the cardiac cell’s proteasome, the mechanism for degrading harmful proteins. This leads to toxic buildup and eventually to the death of cardiac cells.  I don’t know what “proteasome” means…but I do know what the other points mean, and, to be honest, the first and second findings are bad enough.

The study suggested that possibly taking vitamin C (an anti-oxidant, all anti-oxidants help fight the effects of reactive oxygen species) before you take your NSAID may help reduce the possible side effects related to cardiac tissue.  If that’s the case then it would stand to reason that taking ANY anti-inflammatories (such as vitamin E, lipoic acid and Coq-10) would aid in preventing the side effects of NSAID as it relates to ROS’.

Bottom line – if your taking NSAIDS on a regular basis…stop!  The NSAID is only masking your pain and potentially causing massive damage to your heart.  Instead of taking something to mask the pain, fix the issue causing your pain!

We find that often times joint pain can be reduced (and sometimes eliminated) by simple getting stronger and more flexible.  It’s amazing what strength training twice a week and stretching a few days can do for you!

To read the full story click here.

To check out the study click here.

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